• Musculoskeletal pain affects the muscles, bones, ligaments, tendons, and joints, often resulting from injury, strain, or chronic conditions such as arthritis.
• Role of Cannabinoids: THC and CBD may both play a role in managing musculoskeletal pain. THC's analgesic properties may help alleviate pain sensations, while CBD's anti-inflammatory effects may reduce inflammation and associated discomfort. Additionally, THC may help promote muscle relaxation and relieve muscle spasms.

Cannabis and Fibromyalgia

Individuals with fibromyalgia may encounter symptoms such as pain, headaches, and nausea, among others. Several studies have indicated that the active components of cannabis can enhance these symptoms in certain individuals.

Medical cannabis has been shown to provide relief to patients with fibromyalgia, a chronic pain disorder that is characterized by widespread musculoskeletal pain, fatigue, sleep disturbances, and tenderness in localized areas. Medical cannabis can help alleviate the pain associated with fibromyalgia by interacting with the body's endocannabinoid system. It plays a key role in regulating pain perception, inflammation, and mood.

Cannabis contains compounds called cannabinoids, the most well-known of which are tetrahydrocannabinol (THC) and cannabidiol (CBD). THC is the psychoactive compound in cannabis, while CBD is not. Studies have shown that both THC and CBD can help relieve pain associated with fibromyalgia. THC can reduce pain by activating the body's CB1 receptors in the central nervous system, while CBD can reduce inflammation and pain by acting on multiple pathways in the body.

In addition to pain relief, medical cannabis can also help improve sleep and mood in patients with fibromyalgia. Studies have shown that medical cannabis can help improve sleep quality, reduce anxiety and depression, and improve the overall quality of life in patients with chronic pain disorders.

What Studies Exist to Support the Use of Cannabis Against Fibromyalgia?

There have been some studies conducted to investigate the potential benefits of using CBD for Fibromyalgia. However, more research is needed to fully understand its efficacy and safety.

​​”Use of cannabis and cannabinoids for pain relief in fibromyalgia has shown great potential and maybe a source of hope for those suffering from chronic pain associated with this condition, and for the physicians treating them; however, benefits need to be weighed against the harmful effects, and more research into this area should be conducted, for longer periods, to assess for long-term efficacy, adverse effects, and dependence,” states a 2021 study titled ‘A Systematic Review of Fibromyalgia and Recent Advancements in Treatment: Is Medicinal Cannabis a New Hope?’

In a 2018 study, ‘Medical Cannabis for the Treatment of Fibromyalgia’ medical cannabis treatment had a significant favourable effect on patients with fibromyalgia, with few adverse effects.

Another 2011 journal article, ‘Cannabis Use in Patients with Fibromyalgia: Effect on Symptoms Relief and Health-Related Quality of Life' states that the use of cannabis was associated with beneficial effects on some Fibromyalgia symptoms.

It is important to note that these studies have limitations and further research is needed to fully understand the potential benefits and risks of using CBD for Fibromyalgia.

Does cannabis for fibromyalgia have side effects?

The side effects of using medical cannabis for pain, palliative, and cancer care can vary depending on the individual, the method of use, the dosage, and the type of cannabis used.

It can range from Psychotropic effects like euphoria, drowsiness, dizziness, and confusion to cognitive ones including issues related to memory, attention, and reaction time. Besides, smoking or inhaling cannabis can cause respiratory irritation, coughing, and bronchitis. This can be a concern for patients with preexisting lung conditions.

Cannabis can also cause changes in heart rate and blood pressure, which can be problematic for patients with cardiovascular disease and gastrointestinal discomfort, including nausea, vomiting, and diarrhoea.

Key takeaways

• Medical cannabis has been shown to provide relief to patients with fibromyalgia by interacting with the body's endocannabinoid system, which plays a key role in regulating pain perception, inflammation, and mood.

• Cannabis contains cannabinoids, including THC and CBD, which can help relieve pain associated with fibromyalgia.

• Studies on the efficacy and safety of using CBD for fibromyalgia have been conducted, with some showing significant reductions in pain, stiffness, and improvements in sleep quality and overall well-being. However, further research is still needed to fully understand the potential benefits and risks of using CBD for fibromyalgia.

Please note: Medical cannabis is not a cure for fibromyalgia, and its effectiveness can vary depending on the individual. It's also important to work with a healthcare provider who is knowledgeable about medical cannabis and can help determine the appropriate dosage and administration method for each patient.