Medical Cannabis Against Parkinson's Disease

Medical cannabis, specifically cannabinoids like THC and CBD, may offer potential benefits in managing certain symptoms associated with Parkinson's disease. These symptoms can include tremors, muscle stiffness, pain, sleep disturbances, and non-motor symptoms such as anxiety and depression. Some individuals with Parkinson's have reported that cannabis helps alleviate these symptoms and improves their overall quality of life.

Some research suggests that cannabinoids may have a positive impact on motor control in Parkinson's disease. Cannabinoids interact with the endocannabinoid system, which plays a role in regulating movement and coordination. While more research is needed to understand the specific mechanisms involved, cannabinoids have been shown to have the potential in improving motor symptoms.

Parkinson's disease is not solely characterized by motor symptoms but also involves non-motor symptoms like sleep disturbances, mood changes, and cognitive impairments. Some anecdotal evidence and preliminary research suggest that medical cannabis may help alleviate these non-motor symptoms, although more studies are needed to establish its effectiveness.

What Studies Exist to Support the Use of Cannabis Treatment for Parkinson's Disease?

A 2019 study review titled ‘​​Pros and Cons of Marijuana in Treatment of Parkinson’s Disease’ showed promise in improving various PD symptoms, including bradykinesia, tremor, rigidity, depression, sleep disturbances, and pain. However, it's important to note that cannabis use can have short-term and long-term effects, including potential cognitive problems. Long-term use of cannabis may be necessary to observe significant results, but it also poses the risk of dependence on an illicit drug.

A 2014 study found that within 30 minutes, the participants experienced improvements in sleep, tremors, and pain. This suggests that cannabis may have a rapid and positive impact on these specific symptoms of PD. However, it is important to note that this was a small study and more research is needed to further explore the potential benefits and long-term effects of cannabis in treating Parkinson's disease.

Does cannabis for Parkinson's disease have side effects?

The side effects of using medical cannabis for pain, palliative, and cancer care can vary depending on the individual, the method of use, the dosage, and the type of cannabis used. 

It can range from Psychotropic effects like euphoria, drowsiness, dizziness, and confusion to cognitive ones including issues related to memory, attention, and reaction time. Besides, smoking or inhaling cannabis can cause respiratory irritation, coughing, and bronchitis. This can be a concern for patients with preexisting lung conditions.

Cannabis can also cause changes in heart rate and blood pressure, which can be problematic for patients with cardiovascular disease and gastrointestinal discomfort, including nausea, vomiting, and diarrhea.

Key takeaways

• Medical cannabis, specifically cannabinoids like THC and CBD, may offer potential benefits in managing symptoms associated with Parkinson's disease, including tremors, muscle stiffness, pain, sleep disturbances, and non-motor symptoms like anxiety and depression.

• Some research suggests that cannabinoids may have a positive impact on motor control in Parkinson's disease by interacting with the endocannabinoid system involved in regulating movement and coordination.

• Medical cannabis may also have the potential to alleviate non-motor symptoms such as sleep disturbances, mood changes, and cognitive impairments, although further research is needed to establish its effectiveness in these areas.

Please note: As with any medical treatment, it is important to consult with healthcare professionals experienced in medical cannabis and Parkinson's disease before considering its use. They can provide guidance, assess individual suitability, and help determine the appropriate dosage and administration methods based on the person's specific condition and medical history.