Medical Cannabis Against Psoriasis

Psoriasis is a chronic autoimmune condition characterized by red, scaly patches of skin. While there is limited research on the use of medical cannabis specifically for psoriasis, some studies have suggested that cannabinoids found in cannabis may have anti-inflammatory and immune-modulating properties, which could be beneficial for individuals with psoriasis.

One study published in the Journal of Dermatological Science in 2007 found that cannabinoids inhibited the buildup of skin cells and reduced inflammation in human skin cells in vitro. Another study published in the Journal of the American Academy of Dermatology in 2017 found that a synthetic cannabinoid cream was effective in reducing the severity of psoriasis symptoms in human subjects.

In addition to the potential anti-inflammatory effects of cannabinoids, some studies suggest that cannabis may also help alleviate the psychological distress associated with psoriasis. Psoriasis is often associated with depression, anxiety, and poor quality of life, and some individuals with psoriasis report using cannabis to help manage these symptoms.

What Studies Exist to Support the Use of Cannabis for Psoriasis?

A 2007 study’s findings suggest that although Cannabinoid receptors may play a minor role in keratinocyte proliferation, they do not substantially contribute to this process. However, the results demonstrate that cannabinoids can impede keratinocyte proliferation, indicating a possible use for cannabinoids in the management of psoriasis.

A 2017 paper titled ‘Cannabis for Refractory Psoriasis-High Hopes for a Novel Treatment and a Literature Review’, provides evidence to suggest that cannabinoids could be a beneficial therapy for psoriasis. 

A recent 2020 review paper states that cannabis has been shown to potentially slow down the excessive growth of keratinocytes, which are immature skin cells commonly found in individuals with psoriasis. Studies have suggested that cannabinoids and their receptors may play a role in regulating and reducing the production of these immature skin cells.

Does cannabis for psoriasis have side effects?

The side effects of using medical cannabis for pain, palliative, and cancer care can vary depending on the individual, the method of use, the dosage, and the type of cannabis used. 

It can range from Psychotropic effects like euphoria, drowsiness, dizziness, and confusion to cognitive ones including issues related to memory, attention, and reaction time. Besides, smoking or inhaling cannabis can cause respiratory irritation, coughing, and bronchitis. This can be a concern for patients with preexisting lung conditions.

Cannabis can also cause changes in heart rate and blood pressure, which can be problematic for patients with cardiovascular disease and gastrointestinal discomfort, including nausea, vomiting, and diarrhea.

Key takeaways

• Psoriasis is a chronic autoimmune condition characterized by red, scaly patches of skin, and limited research on the use of medical cannabis specifically for psoriasis has been conducted.

• Studies suggest that cannabinoids found in cannabis may have anti-inflammatory and immune-modulating properties that could be beneficial for individuals with psoriasis.

• Some studies have found that cannabinoids can impede the buildup of skin cells and reduce inflammation in human skin cells in vitro, and a synthetic cannabinoid cream was effective in reducing the severity of psoriasis symptoms in human subjects.

• Cannabis may also help alleviate the psychological distress associated with psoriasis, such as depression, anxiety, and poor quality of life.

Please note: It's important to note that while some studies suggest that medical cannabis may be helpful for psoriasis, more research is needed to fully understand the potential benefits and risks, as well as the optimal dosing and delivery methods for different individuals. Individuals considering using medical cannabis for psoriasis should consult with a healthcare provider familiar with medical cannabis to determine if it may be an appropriate treatment option for them.