Cannabis Against Peripheral Neuropathy

Medical cannabis may help with peripheral neuropathy through its interaction with the endocannabinoid system, which plays a role in regulating various bodily functions, including pain perception and inflammation. Cannabinoids found in medical cannabis, such as THC and CBD, can interact with the body's endocannabinoid system and may have analgesic, anti-inflammatory, and neuroprotective effects.

Studies suggest that medical cannabis can help alleviate pain and improve sleep quality in individuals with chronic pain conditions, including peripheral neuropathy. Additionally, medical cannabis may help reduce inflammation and oxidative stress, which can contribute to nerve damage in peripheral neuropathy.

However, it is important to note that more research is needed to fully understand the mechanisms by which medical cannabis may help with peripheral neuropathy and to determine optimal dosing, delivery methods, and potential side effects. Medical cannabis should only be used under the guidance of a healthcare provider and in conjunction with traditional treatments for peripheral neuropathy.

What Studies Exist to Support the Use of Cannabis for Peripheral Neuropathy?

The article ‘Medicinal Cannabis and Painful Sensory Neuropathy’ discusses the potential benefits and risks of using medical cannabis as a treatment for painful sensory neuropathy, a type of nerve damage that causes chronic pain in the feet, legs, and hands.

The authors note that while there is limited clinical evidence to support the use of medical cannabis for this condition, some patients have reported significant pain relief and improved quality of life with its use. The article also reviews the various cannabinoids found in medical cannabis, such as THC and CBD, and their potential mechanisms of action in reducing neuropathic pain.

The authors highlight the need for further research on the safety and efficacy of medical cannabis for painful sensory neuropathy, including studies that compare it to traditional pain medications. 

Does cannabis for peripheral neuropathy have side effects?

The side effects of using medical cannabis for pain, palliative, and cancer care can vary depending on the individual, the method of use, the dosage, and the type of cannabis used. 

It can range from Psychotropic effects like euphoria, drowsiness, dizziness, and confusion to cognitive ones including issues related to memory, attention, and reaction time. Besides, smoking or inhaling cannabis can cause respiratory irritation, coughing, and bronchitis. This can be a concern for patients with preexisting lung conditions.

Cannabis can also cause changes in heart rate and blood pressure, which can be problematic for patients with cardiovascular disease and gastrointestinal discomfort, including nausea, vomiting, and diarrhea.

Key takeaways

• Studies suggest that medical cannabis may be effective in reducing pain associated with peripheral neuropathy. For example, a 2015 review published in the Journal of Neurology found that cannabinoids may be effective in reducing neuropathic pain, including that caused by peripheral neuropathy.

• Cannabinoids found in medical cannabis, such as THC and CBD, interact with the body's endocannabinoid system and may have anti-inflammatory and neuroprotective effects, which could potentially benefit individuals with peripheral neuropathy.

• Medical cannabis should only be used under the guidance of a healthcare provider and in conjunction with traditional treatments for peripheral neuropathy. It is not a substitute for other treatments, and there may be side effects associated with its use.